ASSIGNMENT OF STRUCTURAL BETA-GALACTOSIDASE LOCI TO HUMAN CHROMOSOME-3 AND CHROMOSOME-22

被引：6

作者：

DEWIT, J

HOEKSEMA, HL

BOOTSMA, D

WESTERVELD, A

机构：

[1] Department of Cell Biology and Genetics, Erasmus University, Rotterdam

来源：

HUMAN GENETICS | 1979年 / 51卷 / 03期

关键词：

D O I：

10.1007/BF00283392

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Hybrid cell lines isolated after fusions between Chinese hamster E36 cells and normal human white blood cells were analyzed for human β-galactosidase isoenzymes and for human chromosomes, especially 3, 12, and 22, the candidates for bearing a β-galactosidase locus. Results of neuraminidase treatment of the cell lysates and immunological studies showed that in man two structural β-galactosidase loci are present and can be assigned to chromosomes 3 and 22. No correlation was found between the expression of human β-galactosidase and the presence of human chromosome 12. © 1979 Springer-Verlag.

引用

页码：259 / 267

页数：9

共 23 条

[1]

BOOTSMA D, 1977, 4TH INT WORKSH HUM G

[2]

BRUNS GAP, 1977, 4TH INT WORKSH HUM G

[3]

FERGUSONSMITH MA, 1977, 4TH INT WORKSH HUM G

[4] GENETIC-HETEROGENEITY IN GM1-GANGLIOSIDOSIS [J].