WIDESPREAD TISSUE DISTRIBUTION OF RABBIT CALRETICULIN, A NONMUSCLE FUNCTIONAL ANALOG OF CALSEQUESTRIN

被引：24

作者：

THARIN, S

DZIAK, E

MICHALAK, M

OPAS, M

机构：

[1] UNIV TORONTO, DEPT ANAT & CELL BIOL, TORONTO M5S 1A8, ONTARIO, CANADA

[2] UNIV ALBERTA, CARDIOVASC DIS RES GRP, EDMONTON T6G 2S2, ALBERTA, CANADA

[3] UNIV ALBERTA, DEPT BIOCHEM, EDMONTON T6G 2S2, ALBERTA, CANADA

来源：

CELL AND TISSUE RESEARCH | 1992年 / 269卷 / 01期

关键词：

CALRETICULIN; ENDOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM; CALCIUM-BINDING PROTEINS; RABBIT (LAGOMORPHA);

D O I：

10.1007/BF00384723

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Calreticulin was identified in a variety of rabbit tissues by Western blot analysis. Indirect immunofluorescence studies on cultured cells or frozen sections from the corresponding tissues revealed that the protein was distributed to the endoplasmic reticulum or sarcoplasmic reticulum. Calreticulin was found to be an abundant calcium-binding protein in non-muscle and smooth muscle cells and a constituent calcium-binding protein in cardiac and skeletal muscle. From the immunoblot data, calreticulin may exist as an isoform in rabbit neural retina. The present study establishes the ubiquity of calreticulin in intracellular calcium binding.

引用

页码：29 / 37

页数：9

共 48 条

[1]

BAKSH S, 1991, J BIOL CHEM, V266, P21458

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] INTRACELLULAR CALCIUM HOMEOSTASIS [J].

CARAFOLI, E .

ANNUAL REVIEW OF BIOCHEMISTRY, 1987, 56 :395-433

[4] BIOCHEMISTRY AND BIOPHYSICS OF EXCITATION-CONTRACTION COUPLING [J].

FLEISCHER, S ;

INUI, M .

ANNUAL REVIEW OF BIOPHYSICS AND BIOPHYSICAL CHEMISTRY, 1989, 18 :333-364

[5] AMINO-ACID-SEQUENCE OF RABBIT FAST-TWITCH SKELETAL-MUSCLE CALSEQUESTRIN DEDUCED FROM CDNA AND PEPTIDE SEQUENCING [J].

FLIEGEL, L ;

OHNISHI, M ;

CARPENTER, MR ;

KHANNA, VK ;

REITHMEIER, RAF ;

MACLENNAN, DH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (05) :1167-1171

[6]

FLIEGEL L, 1989, J BIOL CHEM, V264, P21522

[7] THE HIGH-AFFINITY CALCIUM-BINDING PROTEIN OF SARCOPLASMIC-RETICULUM - TISSUE DISTRIBUTION, AND HOMOLOGY WITH CALREGULIN [J].

FLIEGEL, L ;

BURNS, K ;

OPAS, M ;

MICHALAK, M .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 982 (01) :1-8

[8] IMMUNOCYTOCHEMISTRY OF CALCIOSOMES IN LIVER AND PANCREAS [J].

HASHIMOTO, S ;

BRUNO, B ;

LEW, DP ;

POZZAN, T ;

VOLPE, P ;

MELDOLESI, J .

JOURNAL OF CELL BIOLOGY, 1988, 107 (06) :2523-2531

[9]

KRAUSE KH, 1989, J BIOL CHEM, V264, P4269

[10]

KRETSINGER RH, 1973, J BIOL CHEM, V248, P3313

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