HUMORAL IMMUNE-RESPONSES IN EXPERIMENTAL GINGIVITIS IN RATS

被引：2
作者：
KONAKAJIMA, Y [1 ]
TANI, A [1 ]
OHURA, K [1 ]
SHINOHARA, M [1 ]
OGATA, K [1 ]
MORI, M [1 ]
SAGAWA, H [1 ]
机构：
[1] OSAKA DENT UNIV,DEPT PHARMACOL,CHUO KU,OSAKA 540,JAPAN
来源：
ARCHIVES OF ORAL BIOLOGY | 1990年 / 35卷
关键词：
GINGIVITIS; IMMUNOFLUORESCENCE DENTAL PLAQUE; ANTIBODY FORMATION; RAT;
D O I：
10.1016/0003-9969(90)90153-2
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Serum IgG, IgM, and IgA antibody levels to extracts of rat dental plaque and five oral bacteria (Haemophilus actinomycetemcomitans Y-4, Bacteroides gingivalis 381, Bact. intermedius ATCC 25261, Capnocytophaga sp. M-12, Eikenella corrodens ODU) were determined by ELISA. In addition, the presence of rat dental plaque and oral bacterial components in the inflamed gingival tissue was studied using immunofluorescence techniques. Serum and gingival tissue samples were obtained from ODU plaque-susceptible and plaque-resistant rats. In several susceptible rate, IgG, IgM, and IgA antibodies against dental plaque and oral bacteria were detected. There was correlation between the levels of IgG antibody to dental plaque and pocket probing depth, but not between pocket probing depth and the levels of IgM and IgA. Furthermore, components of rat dental plaque and oral bacteria were detected in the inflamed gingival tissue.
引用
收藏
页码：S181 / S183
页数：3
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