PREVALENCE OF HPV IN A MELBOURNE FEMALE STD POPULATION - COMPARISON OF RNA AND DNA PROBES IN DETECTING HPV BY DOT-BLOT HYBRIDIZATION

被引：4

作者：

BORG, AJ

MEDLEY, G

GARLAND, SM

机构：

[1] Department of Microbiology, Royal Women's Hospital, Carlton, Victoria

[2] Victorian Cytology Service, Royal Women's Hospital, Carlton, Victoria

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 1993年 / 4卷 / 03期

关键词：

HUMAN PAPILLOMAVIRUS; DOT BLOT; VIRAPAP VIRATYPE(TM);

D O I：

10.1177/095646249300400307

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A total of 377 women, consecutively selected as first attenders to a sexually transmitted diseases clinic in Melbourne, Australia, were examined for overt Condylomata acuminata and were screened for genital HPV DNA types 6, 11, 16, 18, 31, 33 and (35) using 2 dot blot hybridization methods. Overall, there was a 90% positivity correlation between the 2 methods with HPV DNA being detected in 12% of ectocervical samples. Overt warts were found in 15% of the women and HPV DNA was detected at the cervix in 35% with cytology predicting HPV with or without dysplasia in 27%. Thirteen percent had a past history of warts but none on examination and HPV DNA was evident in 16% while 18% had cytological features of HPV. Those with no warts evident and no past history of warts had both HPV DNA and cytological features of HPV in 7%.

引用

页码：159 / 164

页数：6

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