OVERVIEW OF THE STUDY IN RELATION TO PROTOCOL DESIGN FOR THE RODENT BONE-MARROW MICRONUCLEUS ASSAY

被引:17
作者
ASHBY, J
TINWELL, H
GULATI, D
HEDDLE, JA
机构
[1] ENVIRONM HLTH RES & TESTING INC,LEXINGTON,KY
[2] YORK UNIV,DOWNSVIEW M3J 1P3,ONTARIO,CANADA
来源
MUTATION RESEARCH | 1990年 / 234卷 / 3-4期
关键词
Micronucleus assay; Multiple dosing; Protocol design; Rodent genotoxicity; Toxicity;
D O I
10.1016/0165-1161(90)90018-J
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:223 / 248
页数:26
相关论文
共 27 条
  • [21] Genotoxicity assessment of NIM-76 and its formulation (pessary) in an in vitro Ames Salmonella/microsome assay and in vivo mouse bone marrow micronucleus test
    Vijayan, Vinod
    Meshram, Ghansham P.
    DRUG AND CHEMICAL TOXICOLOGY, 2013, 36 (04) : 430 - 434
  • [22] Evaluation of the rodent micronucleus assay by a 28-day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)-Mammalian Mutagenicity Study Group (MMS)
    Hamada, S
    Sutou, S
    Morita, T
    Wakata, A
    Asanami, S
    Hosoya, S
    Ozawa, S
    Kondo, K
    Nakajima, M
    Shimada, H
    Osawa, K
    Kondo, Y
    Asano, N
    Sato, S
    Tamura, H
    Yajima, N
    Marshall, R
    Moore, C
    Blakey, DH
    Schechtman, LM
    Weaver, JL
    Torous, DK
    Proudlock, R
    Ito, S
    Namiki, C
    Hayashi, M
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2001, 37 (02) : 93 - 110
  • [23] 5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study
    Vermes, A
    Guchelaar, HJ
    van Kuilenburg, ABP
    Dankert, J
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2002, 16 (01) : 39 - 47
  • [24] Refinement and Optimisation of the Rat CFU-GM Assay to Incorporate the Use of Cryopreserved Bone-marrow Cells for In Vitro Toxicology Applications
    Pessina, Augusto
    Bonomi, Arianna
    Baglio, Carolina
    Cavicchini, Loredana
    Gribaldo, Laura
    ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2009, 37 (04): : 417 - 425
  • [25] Activity of a nitroalkene derivative, 1-(5-bromofur-2-il)-2-bromo-2-nitroethene, in the Salmonella/microsome assay and the mouse bone marrow micronucleus test
    Ramos, A
    Vizoso, A
    Edreira, A
    Betancourt, J
    Decalo, M
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 1997, 390 (03) : 233 - 238
  • [26] Genotoxic and chemopreventive potentials of ethanol leaves extract of Annona muricata on N-Ethyl-N-Nitrosourea-induced pro-leukaemia carcinogen in mice model by bone marrow micronucleus assay
    Bamisaye, Oluwaseyi
    Fashina, Anthony
    Abdulraheem, Fatai
    Akanni, Olufemi Emmanuel
    Olufemi, Fadiora S.
    JOURNAL OF MEDICAL SCIENCE, 2024, 91 (04): : 287 - 295
  • [27] Genotoxic and chemopreventive potentials of ethanol leaves extract of Annona muricata on N-Ethyl-N-Nitrosourea-induced pro-leukaemia carcinogen in mice model by bone marrow micronucleus assay
    Bamisaye, Oluwaseyi
    Fashina, Anthony
    Abdulraheem, Fatai
    Akanni, Olufemi Emmanuel
    Olufemi, Fadiora S.
    JOURNAL OF MEDICAL SCIENCE, 2022, 91 (03): : 287 - 295