ENANTIOSELECTIVE MICHAEL-MUKAIYAMA ADDITIONS OF SILYLKETENE ACETALS TO 2-CARBOXYCYCLOPENTENONES PROMOTED BY CHIRAL TI COMPLEXES

被引：26

作者：

BERNARDI, A

KARAMFILOVA, K

BOSCHIN, G

SCOLASTICO, C

机构：

[1] Dipartimento di Chimica Organica e Industriale, Centro CNR per lo Studio delle Sostanze Organiche e Naturali, 20133 Milano

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 08期

关键词：

D O I：

10.1016/0040-4039(94)02478-T

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The conjugate addition of t-butylpropionate silylketeneacetal 2 to 2-carboxycyclopentenones 3a-b promoted by TADDOL-derived Ti chlorides gives the ketoacid 6 with excellent d.e. and e.e. up to 47%.

引用

页码：1363 / 1364

页数：2

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