INHIBITION OF THE EFFECTS OF THROMBIN ON GUINEA-PIG PLATELETS BY THE DIACYLGLYCEROL LIPASE INHIBITOR RHC-80267

被引：6

作者：

AMIN, D ^{[1
]}

SUTHERLAND, CA ^{[1
]}

KHANDWALA, AS ^{[1
]}

JAMALL, IS ^{[1
]}

KAPOOR, AL ^{[1
]}

机构：

[1] RORER GRP INC,DIV RES & DEV,TUCKAHOE,NY 10701

来源：

THROMBOSIS RESEARCH | 1986年 / 44卷 / 01期

关键词：

D O I：

10.1016/0049-3848(86)90182-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：75 / 84

页数：10

共 21 条

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[2] SELECTIVE RELEASE OF ARCHIDONIC ACID FROM PHOSPHOLIPIDS OF HUMAN PLATELETS IN RESPONSE TO THROMBIN [J].

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SMITH, JB ;

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[3] PHOSPHOLIPASE A2 ACTIVITY OF GUINEA-PIG ISOLATED PERFUSED LUNGS - STIMULATION, AND INHIBITION BY ANTI-INFLAMMATORY STEROIDS [J].

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FLOWER, RJ ;

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VANE, JR .

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[4] RHC-80267 DOES NOT INHIBIT THE DIGLYCERIDE LIPASE PATHWAY IN INTACT PLATELETS [J].

BROSS, TE ;

PRESCOTT, SM ;

MAJERUS, PW .

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[5] DIGLYCERIDE MONOGLYCERIDE LIPASES PATHWAY IS NOT ESSENTIAL FOR ARACHIDONATE RELEASE IN THROMBIN-ACTIVATED HUMAN-PLATELETS [J].

CHAU, LY ;

TAI, HH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 113 (01) :241-247

[6]

DIXON JF, 1984, J BIOL CHEM, V259, P4418

[7]

GARRISON JC, 1985, ANNU REP MED CHEM, V20, P227

[8]

LAPETINA EG, 1981, J BIOL CHEM, V256, P5037

[9] THE ROLE OF PHOSPHOLIPASE-C IN PLATELET RESPONSES [J].

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SIESS, W .

LIFE SCIENCES, 1983, 33 (11) :1011-1018

[10] STIMULATION OF PHOSPHATIDIC-ACID PRODUCTION IN PLATELETS PRECEDES THE FORMATION OF ARACHIDONATE AND PARALLELS THE RELEASE OF SEROTONIN [J].

LAPETINA, EG ;

CUATRECASAS, P .

BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 573 (02) :394-402

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