RADISH, A DROSOPHILA MUTANT DEFICIENT IN CONSOLIDATED MEMORY

被引:116
作者
FOLKERS, E [1 ]
DRAIN, P [1 ]
QUINN, WG [1 ]
机构
[1] MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA
关键词
D O I
10.1073/pnas.90.17.8123
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We have characterized the behavior and genetics of the Drosophila mutant radish (rsh gene). Initial learning of radish flies in two olfactory discrimination tests is high, but subsequent memory decays rapidly at both early and late times after training. Anesthesia-resistant memory (consolidated memory) is undetectable in radish flies 3 hr after training. The mutant shows normal locomotor activity and normal sensitivity to the odor cues and electric-shock reinforcement used in the learning tests. The radish gene maps within a 180-kb interval in the 11D-E region of the X chromosome.
引用
收藏
页码:8123 / 8127
页数:5
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