FAMILIAL AUTOIMMUNE MYASTHENIA-GRAVIS - REPORT OF 4 FAMILIES

被引：18
作者：
EVOLI, A
BATOCCHI, AP
ZELANO, G
UNCINI, A
PALMISANI, MT
TONALI, P
机构：
[1] UNIV CATTOLICA SACRO CUORE, INST ANAT, I-00168 ROME, ITALY
[2] UNIV CHIETI, INST NEUROL, CHIETI, ITALY
[3] CSS HOSP, IRCCS, ROTONDO, ITALY
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1995年 / 58卷 / 06期
关键词：
FAMILIAL MYASTHENIA GRAVIS; HLA; ACETYLCHOLINE RECEPTOR ANTIBODY;
D O I：
10.1136/jnnp.58.6.729
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Four families each with two patients with autoimmune myasthenia gravis or related conditions are reported. All clinical forms of myasthenia gravis were represented and different disease types were found within the same family. Either one or two generations could be affected and no association with a single HLA haplotype was found. The frequency of familial autoimmune myasthenia gravis is very low and the genetic factors involved seem to be different from MHC genes.
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页码：729 / 731
页数：3
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