AUTOSOMAL TRISOMY IN A CHIMPANZEE - RESEMBLANCE TO DOWNS SYNDROME

被引：63

作者：

MCCLURE, HM

BELDEN, KH

PIEPER, WA

JACOBSON, CB

机构：

[1] Departments of Veterinary Pathology and Psychobiology, Yerkes Regional Primate Research Center, Emory University, Atlanta

[2] Reproductive Genetics Unit, Department of Obstetrics and Gynecology, George Washington University School of Medicine, Washington

来源：

SCIENCE | 1969年 / 165卷 / 3897期

关键词：

D O I：

10.1126/science.165.3897.1010

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An infant chimpanzee (Pan troglodytes) with clinical, behavioral, and cytogenetic features similar to those in Down's syndrome is described. The infant shows retarded growth rate, congenital abnormalities, retarded neurologic and postural development, epicanthus, hyperflexibility of the joints, muscle hypotonia, and trisomy of a small acrocentric chromosome.

引用

页码：1010 / &