SYNTHESIS AND 3'-SUBSTITUENT EFFECTS OF SOME 7-ALPHA-METHOXY-1-OXACEPHEMS ON ANTIBACTERIAL ACTIVITY AND ALKALINE-HYDROLYSIS RATES

被引：14
作者：
NARISADA, M
NISHIKAWA, J
WATANABE, F
TERUI, Y
机构：
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 03期
关键词：
D O I：
10.1021/jm00386a013
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：514 / 522
页数：9
相关论文
共 51 条
[1]   IMPROVED SYNTHESIS OF 3'-NOR-1-OXACEPHEMS [J].
AOKI, T ;
MINAMI, K ;
KUBOTA, T ;
HAMASHIMA, Y ;
NAGATA, W .
HETEROCYCLES, 1982, 18 :201-209
[2]   NEW ROUTE TO 3-(SUBSTITUTED) METHYL 1-OXACEPHEMS AND (1-THIA)CEPHEMS FROM 3-EXOMETHYLENE INTERMEDIATES VIA SULFENYL CHLORIDE ADDUCTS [J].
AOKI, T ;
KONOIKE, T ;
ITANI, H ;
TSUJI, T ;
YOSHIOKA, M ;
NAGATA, W .
TETRAHEDRON, 1983, 39 (15) :2515-2526
[3]   INTERACTION OF PENICILLIN WITH BACTERIAL CELL - PENICILLIN-BINDING PROTEINS AND PENICILLIN-SENSITIVE ENZYMES [J].
BLUMBERG, PM ;
STROMINGER, JL .
BACTERIOLOGICAL REVIEWS, 1974, 38 (03) :291-335
[4]  
Boyd D B, 1981, Ann N Y Acad Sci, V367, P531, DOI 10.1111/j.1749-6632.1981.tb50589.x
[5]   LACK OF RELEVANCE OF KINETIC-PARAMETERS FOR EXOCELLULAR DD-PEPTIDASES TO CEPHALOSPORIN MICS [J].
BOYD, DB ;
OTT, JL .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 29 (05) :774-780
[6]   ELECTRONIC-STRUCTURES OF CEPHALOSPORINS AND PENICILLINS .15. INDUCTIVE EFFECT OF THE 3-POSITION SIDE-CHAIN IN CEPHALOSPORINS [J].
BOYD, DB .
JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (01) :63-66
[7]   TRANSITION-STATE STRUCTURES OF A DIPEPTIDE RELATED TO MODE OF ACTION OF BETA-LACTAM ANTIBIOTICS [J].
BOYD, DB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5239-5243
[8]   CONFORMATIONAL ANALOGY BETWEEN BETA-LACTAM ANTIBIOTICS AND TETRAHEDRAL TRANSITION-STATES OF A DIPEPTIDE [J].
BOYD, DB .
JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (05) :533-537
[9]   ELECTRONIC-STRUCTURES OF CEPHALOSPORINS AND PENICILLINS .9. DEPARTURE OF A LEAVING GROUP IN CEPHALOSPORINS [J].
BOYD, DB ;
LUNN, WHW .
JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (07) :778-784
[10]   ELUCIDATING THE LEAVING GROUP EFFECT IN THE BETA-LACTAM RING-OPENING MECHANISM OF CEPHALOSPORINS [J].
BOYD, DB .
JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (06) :886-888
123456