1. This mini review highlights the most important findings during three decades of research on biogenic amines in coelenterates. 2. Histochemical, analytic chemical and physiological evidences clearly indicate that dopamine is used as an intercellular messenger in hydrozoans. 3. The colonian anthozoan Renilla, has beta-adrenergic, mechanisms in monitoring bioluminescence and serotoninergic mechanisms in rhythmic contractions.