A NEW TOOL FOR STUDYING PROTEIN-STRUCTURE AND FUNCTION

被引：28
作者：
CORNISH, VW
SCHULTZ, PG
机构：
[1] University of California, Berkeley
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 04期
关键词：
D O I：
10.1016/S0959-440X(94)90224-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A technique that allows for the site-specific incorporation of a large variety of unnatural amino acids into proteins has been developed. This methodology has been used to substitute amino acids with novel electronic, steric. and spectroscopic properties into proteins, providing new insights into the mechanisms of protein stability, enzymatic catalysis and signal transduction.
引用
收藏
页码：601 / 607
页数：7
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