INTERSPECIES DIFFERENCES IN TISSUE DISTRIBUTION OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN BETWEEN COD (GADUS-MORHUA) AND RAINBOW-TROUT (ONCORHYNCHUS-MYKISS)

被引：17
作者：
HEKTOEN, H
INGEBRIGTSEN, K
BREVIK, EM
OEHME, M
机构：
[1] NORWEGIAN COLL VET MED, NATL VET INST, N-0033 OSLO, NORWAY
[2] NORWEGIAN INST AIR RES, N-2001 LILLESTROM, NORWAY
来源：
CHEMOSPHERE | 1992年 / 24卷 / 05期
关键词：
D O I：
10.1016/0045-6535(92)90214-C
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The tissue distribution after administration of a single oral dose (30-mu-g/kg b.wt., corresponding to 12-mu-Ci/kg b.wt.) of C-14-2,3,7,8-dibenzo-p-dioxin (C-14-2,3,7,8-TCDD) was studied in cod (Gadus morhua) and sea-water adapted rainbow trout (Oncorhynchus mykiss) by means of whole-body autoradiography and liquid scintillation counting. Substantial inter-species differences in the distribution pattern were observed. The highest concentrations of C-14-2,3,7,8-TCDD derived radioactivity in the cod were found in the liver and the central nervous system, while the predilection sites for radioactivity in the rainbow trout were the visceral and extravisceral fat depots. The amounts of radioactivity in the liver and the central nervous system of the cod exceeded those of the rainbow trout by a factor of 10 and 7, respectively.
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页码：581 / 587
页数：7
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