DETECTION OF DYNAMIC CHANGES IN CEREBRAL OXYGENATION COUPLED TO NEURONAL FUNCTION DURING MENTAL WORK IN MAN

被引：378

作者：

HOSHI, Y ^{[1
]}

TAMURA, M ^{[1
]}

机构：

[1] HOKKAIDO UNIV,ELECTR SCI RES INST,INTELLIGENT MAT & DEVICE SECT,BIOPHYS GRP,SAPPORO,HOKKAIDO 060,JAPAN

来源：

NEUROSCIENCE LETTERS | 1993年 / 150卷 / 01期

关键词：

NEAR-INFRARED SPECTROPHOTOMETRY; CEREBRAL OXYGENATION; THINKING; CEREBRAL BLOOD FLOW; NEURONAL ACTIVITY; HEMOGLOBIN OXYGENATION STATE;

D O I：

10.1016/0304-3940(93)90094-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Changes in the oxygenation state of brain hemoglobin during mental work were monitored in real time (time resolution: 1 s) using near-infrared spectrophotometry in 14 healthy volunteers. In a younger group (age range 22-30 years, n = 12), the subjects finding difficulty in solving a problem were accompanied by significant increases in both oxygenated hemoglobin and total hemoglobin, while the subjects making a correct answer without difficulty showed no significant changes in hemoglobin oxygenation. When compared with those younger subjects, observations on the older subject demonstrated a decrease in oxygenated hemoglobin and a reciprocal increase in deoxygenated hemoglobin, unaccompanied by changes in total hemoglobin.

引用

页码：5 / 8

页数：4

共 20 条

[1]

BRAZY JE, 1985, PEDIATRICS, V75, P217

[2] NEAR-INFRARED SPECTROSCOPY [J].