ANTHRACYCLINE METABOLITES FROM STREPTOMYCES-VIOLACEUS A262 .3. NEW ANTHRACYCLINE OBELMYCINS PRODUCED BY A VARIANT STRAIN SE2-2385

被引：13

作者：

JOHDO, O ^{[1
]}

WATANABE, Y ^{[1
]}

ISHIKURA, T ^{[1
]}

YOSHIMOTO, A ^{[1
]}

NAGANAWA, H ^{[1
]}

SAWA, T ^{[1
]}

TAKEUCHI, T ^{[1
]}

机构：

[1] INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1991年 / 44卷 / 10期

关键词：

D O I：

10.7164/antibiotics.44.1130

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

New anthracycline antibiotics, designated as obelmycins A, D, E, F and G, were isolated from the culture broth of a variant strain of beta-rhodomycin-producing Streptomyces violaceus A262. identified as beta-isorhodonlycinone glycosides and gamma-isorhodomycinone glycosides and assayed for their in vitro cytotoxicities against murine leukemic L1210 cell culture and the antimicrobial activities in comparison with some known anthracyclines.

引用

页码：1130 / 1140

页数：11

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