A PERCEIVED CLUSTER OF AMYOTROPHIC-LATERAL-SCLEROSIS CASES IN A MASSACHUSETTS COMMUNITY

被引：14

作者：

PROCTOR, SP

FELDMAN, RG

WOLF, PA

BRENT, B

WARTENBERG, D

机构：

[1] BOSTON UNIV,SCH MED,PREVENT MED SECT,BOSTON,MA 02118

[2] VET ADM MED CTR,DEPT NEUROL,BOSTON,MA

[3] BOSTON UNIV,SCH PUBL HLTH,ENVIRONM HLTH SECT,BOSTON,MA 02215

[4] UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,PISCATAWAY,NJ 08854

来源：

NEUROEPIDEMIOLOGY | 1992年 / 11卷 / 4-6期

关键词：

AMYOTROPHIC LATERAL SCLEROSIS; MOTOR NEURON DISEASE; DISEASE CLUSTER; ENVIRONMENTAL RISK; EPIDEMIOLOGY;

D O I：

10.1159/000110941

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We investigated a report of a perceived cluster of amyotrophic lateral sclerosis (ALS) in Middleborough, Mass. Although an increase in ALS incidence was observed [2.51 deaths/100,000 person-years (p-y)], relative to the statewide rate over the years 1969-1985 (1.26/100,000 p-y), it was not statistically significant at the 95 % confidence level. Problems in evaluating possible neurological disease clusters and their association with environmental exposures are presented.

引用

页码：277 / 281

页数：5

共 16 条

[1] GEOGRAPHIC-DISTRIBUTION OF MOTOR NEURON DISEASE AND CORRELATION WITH POSSIBLE ETIOLOGIC FACTORS [J].