HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF PRAZIQUANTEL IN PLASMA AND TISSUES OF CULTURED FISH FOR RESIDUE AND PHARMACOKINETIC STUDIES

被引：7
作者：
HORMAZABAL, V
YNDESTAD, M
机构：
[1] Division of Food Hygiene, Norwegian College of Veterinary Medicine, N-0033, Oslo 1
来源：
JOURNAL OF LIQUID CHROMATOGRAPHY | 1995年 / 18卷 / 03期
关键词：
D O I：
10.1080/10826079508009259
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A simple method for the determination of praziquantel in fish plasma and tissues by HPLC is presented. The samples were extracted with acetone, the organic layer then being separated with diethylether-hexane and evaporated to dryness. The lower limit of quantification was 5, 15, and 20 mu g/kg, for muscle, liver, and plasma, respectively.
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页码：589 / 597
页数：9
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