AN AM1 ANALYSIS OF HYDROGEN-BONDS IN THE TOPA QUINONE COFACTOR OF AMINE OXIDASES

被引：0
作者：
BOSSA, M
BRAHIMI, M
MORPURGO, GO
MORPURGO, L
机构：
[1] UNIV ROMA LA SAPIENZA, DIPARTIMENTO CHIM, I-00185 ROME, ITALY
[2] UNIV ROMA LA SAPIENZA, DIPARTIMENTO SCI BIOCHIM, CNR, CTR BIOL MOLEC, I-00185 ROME, ITALY
[3] HOUARI BOUMEDIENE UNIV, USTHB, ALGIERS, ALGERIA
来源：
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM | 1993年 / 106卷
关键词：
D O I：
暂无
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The 1:1 interaction of 2,5-dihydroxy-p-quinone (DHpQ) with bases such as pyridine, ammonia, water, and methanol was studied by means of the AM1 molecular orbital method. Optimized geometries demonstrated the orientating power of the DHpQ functional group, consisting of one C=O group and the adjacent OH group on the H-bonded base. The implications relating to trihydroxyphenylalanine (TOPA) quinone, the cofactor of amine oxidases containing the same functional group, are discussed.
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页码：269 / 273
页数：5
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