Epithelial sodium channels (ENaC) produce extracellular positive DC potentials in the retinal neuroepithelium

被引：1
|
作者：
Yamashita, Masayuki [1 ]
机构：
[1] Int Univ Hlth & Welf, Ctr Med Sci, 2600-1 Kitakanemaru, Ohtawara 3248501, Japan
来源：
DATA IN BRIEF | 2016年 / 6卷
基金：
日本学术振兴会;
关键词：
D O I：
10.1016/j.dib.2015.11.068
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Positive DC (direct current) potentials were measured in the extracellular space in the retinal neuroepithelium of chick embryos. The positive DC potential was suppressed by amiloride, a blocker for epithelial Na+ channels (ENaC). Amiloride also decreased the resistance of the extracellular space as measured by passing a constant current through a microelectrode. The positive DC potential is necessary for the guidance of retinal ganglion cell axons [1]. (C) 2015 The Authors. Published by Elsevier Inc.
引用
收藏
页码：253 / 256
页数：4
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