Intensity Of Neutrophil Aggregation In Patients With Abdominal Obesity

Neglect of regular physical exertion and excessive food lead in the population of developed countries to a very wide prevalence of abdominal obesity. This condition is very threatening the development of vascular thrombosis. Apparently, with abdominal obesity in the blood aggregation processes intensify. The goal is to evaluate the aggregation of neutrophils in patients with abdominal obesity. We examined 46 patients of the second adulthood (mean age 52.7 +/- 2.2 years) with abdominal obesity. The control group consisted of 26 clinically healthy people of the same age. All the saints in the study of the person gave written informed consent to participate in it. Biochemical, hematological and statistical methods of investigation were used. It became clear that the high incidence of thrombosis of various localizations in abdominal obesity is closely related to the development of neutrophil hyperaggregation. This situation is formed in conditions of abdominal obesity in many respects due to the weakening of antioxidant protection of the plasma with activation of the processes of lipid peroxidation in it. It was found that people with abdominal obesity have an obvious weakening of neutrophil disaggregation. As a result, patients receive a sharply increased risk of thrombosis of any location, which can lead to disability and death.