IMMUNITY TARGETING COMMON CORE ANTIGENS OF GRAM-NEGATIVE BACTERIA

被引：31
作者：
TYLER, JW
CULLOR, JS
SPIER, SJ
SMITH, BP
机构：
[1] Departments of Clinical Pathology, School of Veterinary Medicine, University of California at Davis, Davis, California
[2] Departments of Medicine, School of Veterinary Medicine, University of California at Davis, Davis, California
来源：
JOURNAL OF VETERINARY INTERNAL MEDICINE | 1990年 / 4卷 / 01期
关键词：
D O I：
10.1111/j.1939-1676.1990.tb00870.x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Antibodies against common gram‐negative core antigens can provide protection against environmental, commensual, and contagious bacteria that cause life‐threatening gram‐negative sepsis/endotoxemia. Cross‐protective immunity may be effective against many common livestock diseases, including neonatal coliform septicemia, coliform mastitis, septic metritis, and severe enteritis. The greatest potential benefit of cross‐protective immunity may be realized in the reduction of ill‐thrift and mortality of neonates. The use of active and passive immunization against core antigens common to gram‐negative bacteria has been successful in human beings, laboratory animals, and livestock. Protection has been observed following challenge with either heterologous endotoxin or unrelated, live, virulent gram‐negative bacteria. (Journal of Veterinary Internal Medicine 1990; 4:17–25) Copyright © 1990, Wiley Blackwell. All rights reserved
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页码：17 / 25
页数：9
相关论文
共 112 条
[1]  
Braude AI., Endotoxic immunity, Adv Intern Med, 26, pp. 427-445, (1980)
[2]  
Bennett IL, Beeson PB., The properties and biologic effects of bacterial pyrogens, Medicine, 29, pp. 365-400, (1950)
[3]  
Shenep JL, Barton RP, Morgan KA., Role of antibiotic class in the rate of liberation of endotoxin during therapy for experimental gram‐negative bacterial sepsis, J Infect Dis, 151, pp. 1012-1018, (1985)
[4]  
Shenep JL, Morgan KA., Kinetics of endotoxin release during antibiotic therapy for experimental gram‐negative bacterial sepsis, J Infect Dis, 150, pp. 380-388, (1984)
[5]  
Bourn JM, Siebert FB., The cause of many febrile reactions following intravenous injections: II. The bacteriology of twelve distilled waters, Am J Physiol, 71, pp. 652-659, (1925)
[6]  
Bradley SG., Cellular and molecular mechanisms of action of bacterial endotoxins, Annu Rev Microbiol, 33, pp. 67-94, (1979)
[7]  
Spink W., Braude AI, Castaneda MR, Et al., Aureomycin therapy in humanBrucellosis due to Brucella melitensis, JAMA, 138, pp. 1145-1148, (1948)
[8]  
Borden C., Hale W., Fatal transfusion reactions from massive bacterial contamination of blood, N Engl J Med, 245, pp. 760-765, (1951)
[9]  
Braude AI., Transfusion reactions from massive bacterial contamination of blood, New England Journal of Medicine, 258, pp. 1289-1293, (1958)
[10]  
Brues A., Shear M., Reactions of four patients with advanced malignant tumors to injections of a polysaccharide from Ser‐ratia marcescans culture nitrate, JNCI, 5, pp. 195-208, (1944)
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