HODGKINS-DISEASE - RESULTS OF TREATMENT IN EARLY STAGES

被引：0

作者：

VITALE, V ^{[1
]}

SCIELZO, G ^{[1
]}

RICCI, G ^{[1
]}

TOMASSINI, E ^{[1
]}

MARZIANO, C ^{[1
]}

SIRAGUSA, A ^{[1
]}

VITALI, ML ^{[1
]}

BARRA, S ^{[1
]}

SALUSCIEV, P ^{[1
]}

CORSO, M ^{[1
]}

GUENZI, M ^{[1
]}

BISTOLFI, F ^{[1
]}

机构：

[1] GALLIERA HOSP, DEPT RADIOTHERAPY, I-16128 GENOA, ITALY

来源：

PANMINERVA MEDICA | 1988年 / 30卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This report presents detailed results obtained in 181 patients with stage 1A and B, IIA and B and IIIA Hodgkin''s disease; in these subgroups the overall 10 year survival and disease-free survival were 77% and 67% respectively. In stage I and II patients (considered together) an adverse influence of systemic symptoms was detected (55% vs. 85% 10 year overall survival - p < 0.05). Bulky mediastinal disease was an adverse prognostic factor both for overall survival (89% of patients with positive mediastinum all stages vs. 72% of patients with bulky mediastinum at 5 years - p > 0.01) and relapse free survival (87% vs. 55% at 3 years - p > 0.01). Four cases of acute non-lymphoblastic leukemia and 3 cases of severe aplastic anemia were observed among patients given combined therapy (radiotherapy plus chemotherapy).

引用

页码：144 / 149

页数：6