Vancomycin-Resistant Enterococcus faecium Meningitis Treated with Linezolid: A Case Report and Review of the Literature

被引：1

作者：

Lee, Chang-Seop ^{[1
]}

Park, Seoung-Ju ^{[1
]}

Lee, Yong-Chul ^{[1
]}

Rhee, Yang-Keun ^{[1
]}

Lee, Heung-Bum ^{[1
]}

机构：

[1] Chonbuk Natl Univ, Med Sch & Res Inst Clin Med, Dept Internal Med, Jeonju, South Korea

来源：

INFECTION AND CHEMOTHERAPY | 2010年 / 42卷 / 03期

关键词：

Vancomycin; Enterococcus faecium; Meningitis; Linezolid;

D O I：

10.3947/ic.2010.42.3.194

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Vancomycin-resistant enterococci (VRE) infection is a serious problem because optimal therapy has not been established. Different agents in various combinations, including teicoplanin, chloramphenicol, and quinupristin/dalfopristin, have been used to treat patients with VRE meningitis, but the efficacy of these agents is not satisfactory because of their limited ability to penetrate into the cerebrospinal fluid. We report a case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in a patient with ventriculoperitoneal shunt that was successfully treated with linezolid. We will also review previously reported cases of vancomycin-resistant E. faecium meningitis treated by linezolid.

引用

页码：194 / 197

页数：4

共 18 条

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