ISOENZYMES OF ALANINE AMINOPEPTIDASE AS SPECIFIC PARAMETERS IN DIAGNOSIS OF BILIARY AND PANCREATIC DISEASES

被引：16
作者：
BEIER, L
BEIER, I
HASCHEN, RJ
机构：
来源：
CLINICA CHIMICA ACTA | 1969年 / 24卷 / 03期
关键词：
D O I：
10.1016/0009-8981(69)90112-0
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Alanine aminopeptidase (ANAase) exists in the form of organ-specific isoenzymes, which are separated by agar gel electrophoresis. In normal serum only AN Aase-1 is present. Its increase is a specific and sensitive indication of intra- or extrahepatic cholestasis. There exists a statistically significant correlation between this isoenzyme and alkaline phosphatase. In pancreatic disease, ANAase-2 additionally can be demonstrated. Its diagnostic specificity and sensitivity are much higher than those of α-amylase. © 1969.
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页码：405 / &
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