Adult Primary Spinal Epidural Extraosseous Ewing's Sarcoma: A Case Report and Review of the Literature

被引:6
作者
Bustoros, Mark [1 ]
Thomas, Cheddhi [2 ]
Frenster, Joshua [1 ]
Modrek, Aram S. [1 ]
Bayin, N. Sumru [1 ]
Snuderl, Matija [2 ,3 ,4 ]
Rosen, Gerald [3 ,5 ]
Schiff, Peter B. [3 ,6 ]
Placantonakis, Dimitris G. [1 ,3 ,4 ,7 ]
机构
[1] NYU, Sch Med, Dept Neurosurg, New York, NY 10016 USA
[2] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA
[3] NYU, Langone Med Ctr, Perlmutter Canc Ctr, New York, NY 10016 USA
[4] NYU, Langone Med Ctr, Brain Tumor Ctr, New York, NY 10016 USA
[5] NYU, Sch Med, Dept Med, New York, NY 10016 USA
[6] NYU, Sch Med, Dept Radiat Oncol, New York, NY 10016 USA
[7] NYU, Sch Med, Kimmel Ctr Stem Cell Biol, New York, NY 10016 USA
关键词
D O I
10.1155/2016/1217428
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background. Extraosseous Ewing's sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy. MRI revealed a thoracic extradural mass with no osseous involvement. He underwent surgery for gross total resection of the mass, which was diagnosed as Ewing's sarcoma. He was subsequently treated with chemoradiotherapy. He remains disease-free 1 year after surgery. Review of the literature indicated only 45 previously reported cases of spinal epidural extraosseous Ewing's sarcoma in adults. Conclusions. Extraosseous Ewing's sarcoma in the spinal epidural space is a rare clinical entity that should be included in the differential for spinal epidural masses. Its treatment is multidisciplinary but frequently requires surgical intervention due to compressive neurologic symptoms. Gross total resection appears to correlate with improved outcomes.
引用
收藏
页数:8
相关论文
共 49 条
[1]  
ANGERVALL L, 1975, CANCER, V36, P240, DOI 10.1002/1097-0142(197507)36:1<240::AID-CNCR2820360127>3.0.CO
[2]  
2-H
[3]   Adults with Ewing's sarcoma primitive neuroectodermal tumor - Adverse effect of older age and primary extraosseous disease on outcome [J].
Baldini, EH ;
Demetri, GD ;
Fletcher, CDM ;
Foran, J ;
Marcus, KC ;
Singer, S .
ANNALS OF SURGERY, 1999, 230 (01) :79-86
[4]  
Bostelmann RLM, 2011, P 62 ANN M GERM SOC, V7
[5]   Primary extraosseous Ewing sarcoma of the cervical epidural space - Case illustration [J].
Bozkurt, Gokhan ;
Ayhan, Selim ;
Turk, Ceznh Cagri ;
Akbay, Atilla ;
Soylemezoglu, Figen ;
Palaoglu, Selcuk .
JOURNAL OF NEUROSURGERY-SPINE, 2007, 6 (02) :192-192
[6]   Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up [J].
Casali, Paolo G. ;
Blay, Jean-Yves ;
Bertuzzi, Alexia ;
Bielack, Stefan ;
Bjerkehagen, Bodil ;
Bonvalot, Sylvie ;
Boukovinas, Ioannis ;
Bruzzi, Paolo ;
Dei Tos, Angelo Paolo ;
Dileo, Palma ;
Eriksson, Mikael ;
Fedenko, Alexander ;
Ferrari, Andrea ;
Ferrari, Stefano ;
Gelderblom, Hans ;
Grimer, Robert ;
Gronchi, Alessandro ;
Haas, Rick ;
Hall, Kirsten Sundby ;
Hohenberger, Peter ;
Issels, Rolf ;
Joensuu, Heikki ;
Judson, Ian ;
Le Cesne, Axel ;
Litiere, Saskia ;
Martin-Broto, Javier ;
Merimsky, Ofer ;
Montemurro, Michael ;
Morosi, Carlo ;
Picci, Piero ;
Ray-Coquard, Isabelle ;
Reichardt, Peter ;
Rutkowski, Piotr ;
Schlemmer, Marcus ;
Stacchiotti, Silvia ;
Torri, Valter ;
Trama, Annalisa ;
Van Coevorden, Frits ;
Van der Graaf, Winette ;
Vanel, Daniel ;
Wardelmann, Eva .
ANNALS OF ONCOLOGY, 2014, 25 :113-123
[7]   Intraspinal primitive neuroectodermal tumors: Report of four cases and review of the literature [J].
Chen, Jingyu ;
Song, Jinning ;
Meng, Hui ;
Feng, Hua .
NEUROLOGY INDIA, 2009, 57 (05) :661-668
[8]  
Christie D R, 1997, Australas Radiol, V41, P22, DOI 10.1111/j.1440-1673.1997.tb00463.x
[9]   Intraspinal primitive neuroectodermal tumour:: Report of two cases and review of the literature [J].
Dorfmüller, G ;
Würtz, FG ;
Umschaden, HW ;
Kleinert, R ;
Ambros, PF .
ACTA NEUROCHIRURGICA, 1999, 141 (11) :1169-1175
[10]   Intraspinal primitive neuroectodermal tumor: Imaging findings in six cases [J].
Duan, Xiao-Hui ;
Ban, Xiao-Hua ;
Liu, Bo ;
Zhong, Xiao-Mei ;
Guo, Ruo-Mi ;
Zhang, Fang ;
Liang, Bi-Ling ;
Shen, Jun .
EUROPEAN JOURNAL OF RADIOLOGY, 2011, 80 (02) :426-431