METABOLISM OF PROGESTERONE AND TESTOSTERONE BY BACILLUS-CEREUS STRAIN SOCRANSKY-6M AND STREPTOCOCCUS-MUTANS STRAIN INGBRITT

被引：19

作者：

OJANOTKOHARRI, A

NIKKARI, T

HARRI, MP

PAUNIO, K

机构：

[1] Department of Physiology, University of Turku, Turku

[2] Department of Periodontology, University of Turku, Turku

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1990年 / 5卷 / 04期

关键词：

Bacillus cereus strain Socransky 67; metabolism; progesterone; Streptococcus mutans strain Ingbritt; testosterone;

D O I：

10.1111/j.1399-302X.1990.tb00653.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Bacillus cereus strain Socransky 67 and Streptococcus mutans strain Ingbritt grown overnight in complex medium and then in fresh medium flasks for 5h‐ The bacterial cells in the medium were centrifuged and resuspended; 4‐14C‐Progesterone or 4–14C ‐testosterone was added, and the samples were incubated for 2 h at 37 °C in a shaking water bath. The metabolites were analyzed with column and thin layer chromatography and radioautography and quantified by liquid scintillation counting. On the basis of the metabolites found it was and concluded that B. cereus strain Socransky 67 contains 5a‐steroid hydrogenase. and 3β‐, 17β and 20a‐hydroxysteroid dehydrogenases and probably also steroid hydroxylases, and that S. mutans strain Ingbritt contains 5a‐ and 5β–steroid Wrogenases, and 3a–, 17β– and 20a–hydroxysteroid dehydrogenases. The metabolic activity of B. cereus is several times higher than that of S. mutans. We Suggest that the greater ability of B. cereus to metabolize progesterone and testosterle is probably due to its growth milieu in the gingival sulcus, where it is nearer 1 the gingival tissue. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：237 / 239

页数：3

共 22 条

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