RIBAVIRIN TREATMENT OF THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME (AIDS) AND THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME-RELATED COMPLEX (ARC) - A PHASE-1 STUDY SHOWS TRANSIENT CLINICAL IMPROVEMENT ASSOCIATED WITH SUPPRESSION OF THE HUMAN-IMMUNODEFICIENCY-VIRUS AND ENHANCED LYMPHOCYTE-PROLIFERATION

被引：43

作者：

CRUMPACKER, C

HEAGY, W

BUBLEY, G

MONROE, JE

FINBERG, R

HUSSEY, S

SCHNIPPER, L

LUCEY, D

LEE, TH

MCLANE, MF

ESSEX, M

MULDER, C

机构：

[1] HARVARD THORNDIKE DANA RES LAB, DIV INFECT DIS, BOSTON, MA USA

[2] HARVARD THORNDIKE DANA RES LAB, DIV ONCOL, BOSTON, MA USA

[3] BETH ISRAEL HOSP, DEPT MED, BOSTON, MA 02215 USA

[4] HARVARD UNIV, SCH MED, DANA FARBER CANC INST, INFECT DIS LAB, BOSTON, MA 02115 USA

[5] HARVARD UNIV, SCH PUBL HLTH, DEPT CANC BIOL, BOSTON, MA 02115 USA

[6] UNIV MASSACHUSETTS, MED CTR, DEPT PHARMACOL, WORCESTER, MA 01605 USA

[7] UNIV MASSACHUSETTS, MED CTR, DEPT MOLEC GENET, WORCESTER, MA 01605 USA

[8] UNIV MASSACHUSETTS, MED CTR, DEPT MICROBIOL, WORCESTER, MA 01605 USA

[9] UNIV MASSACHUSETTS, MED CTR, DEPT PEDIAT, WORCESTER, MA 01605 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1987年 / 107卷 / 05期

关键词：

D O I：

10.7326/0003-4819-107-5-664

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：664 / 674

页数：11

共 29 条

[1]

BRODER S, 1985, LANCET, V2, P627

[2]

CRUMPACKER C, 1986, LANCET, V2, P45

[3]

CRUMPACKER CS, 1987, 3 INT C AIDS WASH, P147

[4]

CRUMPACKER CS, 1985, INT C AIDS, P201

[5] SURAMIN - POTENT INHIBITOR OF THE REVERSE-TRANSCRIPTASE OF RNA TUMOR-VIRUSES [J].

DECLERCQ, E .

CANCER LETTERS, 1979, 8 (01) :9-22

[6] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISCHL, MA ;

RICHMAN, DD ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

SCHOOLEY, RT ;

JACKSON, GG ;

DURACK, DT ;

KING, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :185-191

[7]

FRIEDLAND GH, 1987, 3RD P INT C AIDS WAS, P156

[8] FREQUENT DETECTION AND ISOLATION OF CYTOPATHIC RETROVIRUSES (HTLV-III) FROM PATIENTS WITH AIDS AND AT RISK FOR AIDS [J].

GALLO, RC ;

SALAHUDDIN, SZ ;

POPOVIC, M ;

SHEARER, GM ;

KAPLAN, M ;

HAYNES, BF ;

PALKER, TJ ;

REDFIELD, R ;

OLESKE, J ;

SAFAI, B ;

WHITE, G ;

FOSTER, P ;

MARKHAM, PD .

SCIENCE, 1984, 224 (4648) :500-503

[9] DETECTION OF CIRCULAR AND LINEAR HERPESVIRUS DNA-MOLECULES IN MAMMALIAN-CELLS BY GEL-ELECTROPHORESIS [J].

GARDELLA, T ;

MEDVECZKY, P ;

SAIRENJI, T ;

MULDER, C .

JOURNAL OF VIROLOGY, 1984, 50 (01) :248-254

[10] ETIOLOGY OF AIDS - ANTIBODIES TO HUMAN T-CELL LEUKEMIA-VIRUS (TYPE-III) IN HEMOPHILIACS [J].

KITCHEN, LW ;

BARIN, F ;

SULLIVAN, JL ;

MCLANE, MF ;

BRETTLER, DB ;

LEVINE, PH ;

ESSEX, M .

NATURE, 1984, 312 (5992) :367-369

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