CEREBRAL VESSELS HAVE THE CAPACITY TO TRANSPORT SODIUM AND POTASSIUM

被引：81

作者：

EISENBERG, HM ^{[1
]}

SUDDITH, RL ^{[1
]}

机构：

[1] UNIV TEXAS, MED BRANCH, INST MARINE BIOMED, GALVESTON, TX 77550 USA

来源：

SCIENCE | 1979年 / 206卷 / 4422期

关键词：

D O I：

10.1126/science.227060

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The activity of Na+,K+-activated adenosinetriphosphatase and the uptake of a potassium analog, rubidium, were found to be similar in cerebral microvessels and choroid plexus when measured in vitro. This similarity suggests that sodium and potassium concentrations in the nascent brain extracellular fluid are determined by the same active process that regulates their concentration in nascent cerebrospinal fluid. The brain microvessels may thereby play an active role in brain potassium homeostasis and brain extracellular fluid formation. Copyright © 1979 AAAS.

引用

页码：1083 / 1085

页数：3

共 25 条

[1] RELATION OF POTASSIUM CONCENTRATION IN CHOROID-PLEXUS FLUID TO THAT IN PLASMA [J].

AMES, A ;

HIGASHI, K ;

NESBETT, FB .

JOURNAL OF PHYSIOLOGY-LONDON, 1965, 181 (03) :506-&

[2] POLARITY OF BLOOD-BRAIN-BARRIER - NEUTRAL AMINO-ACID TRANSPORT INTO ISOLATED BRAIN CAPILLARIES [J].

BETZ, AL ;

GOLDSTEIN, GW .

SCIENCE, 1978, 202 (4364) :225-227

[3] STUDIES ON SODIUM - POTASSIUM-ACTIVATED ADENOSINETRIPHOSPHATASE .5. CORRELATION OF ENZYME ACTIVITY WITH CATION FLUX IN 6 TISSUES [J].

BONTING, SL ;

CARAVAGGIO, LL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1963, 101 (01) :37-&

[4] TRANSPORT OF POTASSIUM BETWEEN BLOOD CEREBROSPINAL FLUID AND BRAIN [J].

BRADBURY, BW ;

DAVSON, H .

JOURNAL OF PHYSIOLOGY-LONDON, 1965, 181 (01) :151-+

[5] ISOLATED BRAIN MICROVESSELS - PURIFIED, METABOLICALLY ACTIVE PREPARATION FROM BOVINE CEREBRAL-CORTEX [J].

BRENDEL, K ;

MEEZAN, E ;

CARLSON, EC .

SCIENCE, 1974, 185 (4155) :953-955

[6] JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN VERTEBRATE BRAIN [J].

BRIGHTMA.MW ;

REESE, TS .

JOURNAL OF CELL BIOLOGY, 1969, 40 (03) :648-+

[7] STUDIES ON PERMEABILITY OF BLOOD-RETINAL BARRIER .I. ON EXISTENCE DEVELOPMENT AND SITE OF A BLOOD-RETINAL BARRIER [J].

CUNHAVAZ, JG ;

SHAKIB, M ;

ASHTON, N .

BRITISH JOURNAL OF OPHTHALMOLOGY, 1966, 50 (08) :441-&

[8] STUDIES ON RESPIRATORY RESPONSE TO DISTURBANCES OF ACID-BASE BALANCE WITH DEDUCTIONS CONCERNING IONIC COMPOSITION OF CEREBRAL INTERSTITIAL FLUID [J].

FENCL, V ;

MILLER, TB ;

PAPPENHEIMER, JR .

AMERICAN JOURNAL OF PHYSIOLOGY, 1966, 210 (03) :459-+

[9] ISOLATION OF METABOLICALLY ACTIVE CAPILLARIES FROM RAT-BRAIN [J].

GOLDSTEIN, GW ;

WOLINSKY, JS ;

CSEJTEY, J ;

DIAMOND, I .

JOURNAL OF NEUROCHEMISTRY, 1975, 25 (05) :715-+

[10] ISOLATED MICROVESSELS - BLOOD-BRAIN-BARRIER INVITRO [J].

HJELLE, JT ;

BAIRDLAMBERT, J ;

CARDINALE, G ;

SPECTOR, S ;

UDENFRIEND, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (09) :4544-4548

← 1 2 3 →