NUCLEOTIDE EXCISION-REPAIR AND THE LINK WITH TRANSCRIPTION

被引：139
作者：
LEHMANN, AR
机构：
[1] MRC Cell Mutation Unit, University of Sussex, Brighton, BN1 9RR, Faimer
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 10期
关键词：
D O I：
10.1016/S0968-0004(00)89088-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Nucleotide excision repair (NER) uses the products of about 30 genes to remove a damage-containing oligonucleotide from cellular DNA. The transcription factor TFIIH is an essential component of NER, in man, defects in NER can result in three distinct genetic disorders, whose features can be ascribed to abnormalities in DNA repair or transcription.
引用
收藏
页码：402 / 405
页数：4
相关论文
共 29 条
[1]   MAMMALIAN DNA NUCLEOTIDE EXCISION-REPAIR RECONSTITUTED WITH PURIFIED PROTEIN-COMPONENTS [J].
ABOUSSEKHRA, A ;
BIGGERSTAFF, M ;
SHIVJI, MKK ;
VILPO, JA ;
MONCOLLIN, V ;
PODUST, VN ;
PROTIC, M ;
HUBSCHER, U ;
EGLY, JM ;
WOOD, RD .
CELL, 1995, 80 (06) :859-868
[2]   SPECIFIC CLEAVAGE OF MODEL RECOMBINATION AND REPAIR INTERMEDIATES BY THE YEAST RAD1-RAD10 DNA ENDONUCLEASE [J].
BARDWELL, AJ ;
BARDWELL, L ;
TOMKINSON, AE ;
FRIEDBERG, EC .
SCIENCE, 1994, 265 (5181) :2082-2085
[3]   MUTATIONS IN THE XERODERMA-PIGMENTOSUM GROUP-D DNA REPAIR/TRANSCRIPTION GENE IN PATIENTS WITH TRICHOTHIODYSTROPHY [J].
BROUGHTON, BC ;
STEINGRIMSDOTTIR, H ;
WEBER, CA ;
LEHMANN, AR .
NATURE GENETICS, 1994, 7 (02) :189-194
[4]  
BROUGHTON BC, 1995, AM J HUM GENET, V56, P167
[5]   DUAL ROLE OF TFIIH IN DNA EXCISION-REPAIR AND IN TRANSCRIPTION BY RNA-POLYMERASE-II [J].
DRAPKIN, R ;
REARDON, JT ;
ANSARI, A ;
HUANG, JC ;
ZAWEL, L ;
AHN, KJ ;
SANCAR, A ;
REINBERG, D .
NATURE, 1994, 368 (6473) :769-772
[6]  
GREWE M, 1995, J INVEST DERMATOL, V104, P574
[7]   RPA INVOLVEMENT IN THE DAMAGE-RECOGNITION AND INCISION STEPS OF NUCLEOTIDE EXCISION-REPAIR [J].
HE, ZG ;
HENRICKSEN, LA ;
WOLD, MS ;
INGLES, CJ .
NATURE, 1995, 374 (6522) :566-569
[8]   NUCLEOTIDE EXCISION REPAIR .1. FROM ESCHERICHIA-COLI TO YEAST [J].
HOEIJMAKERS, JHJ .
TRENDS IN GENETICS, 1993, 9 (05) :173-177
[9]  
ITIN PH, 1990, J AM ACAD DERMATOL, V20, P705
[10]  
KRIPKE ML, 1994, CANCER RES, V54, P6102
123