IRL-1620, SUCCINYL-[GLU(9),ALA(11,15)]-ENDOTHELIN-1(8-21), A HIGHLY SPECIFIC AGONIST OF THE ET(B) RECEPTOR

被引：27

作者：

JAMES, AF

URADE, Y

WEBB, RL

KARAKI, H

UMEMURA, I

FUJITANI, Y

ODA, K

OKADA, T

LAPPE, RW

TAKAI, M

机构：

[1] CIBA GEIGY JAPAN LTD, INT RES LABS, TAKARAZUKA, HYOGO, JAPAN

[2] CIBA GEIGY CORP, DEPT RES, DIV PHARMACEUT, SUMMIT, NJ 07901 USA

[3] UNIV TOKYO, DEPT VET PHARMACOL, TOKYO, JAPAN

来源：

CARDIOVASCULAR DRUG REVIEWS | 1993年 / 11卷 / 03期

关键词：

IRL; 1620; ENDOTHELIN; ET(B) RECEPTOR; ET(B) AGONIST; VASODILATION; VASOCONSTRICTION;

D O I：

10.1111/j.1527-3466.1993.tb00190.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：253 / 270

页数：18

共 52 条

[1] CLONING AND EXPRESSION OF A CDNA-ENCODING AN ENDOTHELIN RECEPTOR [J].

ARAI, H ;

HORI, S ;

ARAMORI, I ;

OHKUBO, H ;

NAKANISHI, S .

NATURE, 1990, 348 (6303) :730-732

[2] ETB RECEPTORS ON AORTIC SMOOTH-MUSCLE CELLS OF SPONTANEOUSLY HYPERTENSIVE RATS [J].

BATRA, VK ;

MCNEILJ, JR ;

XU, YJ ;

WILSON, TW ;

GOPALAKRISHNAN, V .

AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 264 (02) :C479-C484

[3]

BAZIL MK, 1992, J CARDIOVASC PHARM, V20, P940, DOI 10.1097/00005344-199212000-00011

[4] DISCRIMINATION BETWEEN ETA-RECEPTOR-MEDIATED AND ETB-RECEPTOR-MEDIATED EFFECTS OF ENDOTHELIN-1 AND [ALA1,3,11,15]ENDOTHELIN-1 BY BQ-123 IN THE ANESTHETIZED RAT [J].

BIGAUD, M ;

PELTON, JT .

BRITISH JOURNAL OF PHARMACOLOGY, 1992, 107 (04) :912-918

[5] FORMATION OF ENDOTHELIN BY CULTURED AIRWAY EPITHELIAL-CELLS [J].

BLACK, PN ;

GHATEI, MA ;

TAKAHASHI, K ;

BRETHERTONWATT, D ;

KRAUSZ, T ;

DOLLERY, CT ;

BLOOM, SR .

FEBS LETTERS, 1989, 255 (01) :129-132

[6] A NOVEL ETA-RECEPTOR ANTAGONIST, FR-139317, INHIBITS ENDOTHELIN-INDUCED CONTRACTIONS OF GUINEA-PIG PULMONARY-ARTERIES, BUT NOT TRACHEA [J].

CARDELL, LO ;

UDDMAN, R ;

EDVINSSON, L .

BRITISH JOURNAL OF PHARMACOLOGY, 1993, 108 (02) :448-452

[7] THE ENDOTHELIN ET(B) RECEPTOR MEDIATES BOTH VASODILATION AND VASOCONSTRICTION INVIVO [J].

CLOZEL, M ;

GRAY, GA ;

BREU, V ;

LOFFLER, BM ;

OSTERWALDER, R .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 186 (02) :867-873

[8]

CLOZEL M, IN PRESS J CARDIOV S, V10

[9] DESIGN OF A FUNCTIONAL HEXAPEPTIDE ANTAGONIST OF ENDOTHELIN [J].

CODY, WL ;

DOHERTY, AM ;

HE, JX ;

DEPUE, PL ;

RAPUNDALO, ST ;

HINGORANI, GA ;

MAJOR, TC ;

PANEK, RL ;

DUDLEY, DT ;

HALEEN, SJ ;

LADOUCEUR, D ;

HILL, KE ;

FLYNN, MA ;

REYNOLDS, EE .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (17) :3301-3303

[10] MEDIATION VIA DIFFERENT RECEPTORS OF THE VASOCONSTRICTOR EFFECTS OF ENDOTHELINS AND SARAFOTOXINS IN THE SYSTEMIC CIRCULATION AND RENAL VASCULATURE OF THE ANESTHETIZED RAT [J].

CRISTOL, JP ;

WARNER, TD ;

THIEMERMANN, C ;

VANE, JR .

BRITISH JOURNAL OF PHARMACOLOGY, 1993, 108 (03) :776-779

← 1 2 3 4 5 6 →