GAMMA-DELTA T-CELL DEVELOPMENT

被引：54
作者：
ALLISON, JP
机构：
[1] University of California, Berkeley
来源：
CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 02期
关键词：
D O I：
10.1016/0952-7915(93)90011-G
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Gammadelta T cells consist of multiple lineages of cells with distinct antigen receptor repertoires, tissue localization and function. Recent evidence suggests that the ordered appearance of these sublineages during development is a result of programed rearrangement of V(gamma)-gene segments. It appears that the T-cell receptor repertoire, at least of the gamma(delta) T cells with invariant receptors, is the result of site-directed rearrangement and cellular selection does not play a major role.
引用
收藏
页码：241 / 246
页数：6
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