INCREASED SUPEROXIDE ANION RELEASE BY PERITONEAL-MACROPHAGES IN MICE WITH A CHRONIC INFECTION OF LACTIC-DEHYDROGENASE VIRUS

被引：5

作者：

HAYASHI, T ^{[1
]}

OZAKI, M ^{[1
]}

AMI, Y ^{[1
]}

ONODERA, T ^{[1
]}

YAMAMOTO, H ^{[1
]}

机构：

[1] NATL INST ANIM HLTH,IBARAKI,JAPAN

来源：

JOURNAL OF COMPARATIVE PATHOLOGY | 1992年 / 106卷 / 01期

关键词：

D O I：

10.1016/0021-9975(92)90073-4

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The function of macrophages in mice chronically infected by lactic dehydrogenase virus (LDV) was studied. Superoxide anion (O2-) release was examined by using peritoneal macrophages. O2- release increaed markedly from 3 weeks to 12 months, but not at 1 week post infection. O2- release was 1·2 to 1·5 times greater than in uninfected mice. Increased O2- release from macrophages in LDV-infected mice may explain, at least in part, suppressive effects on tumour growth seen in the chronic phase of infection. © 1992.

引用

页码：93 / 98

页数：6

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