MASS-SPECTROMETRY OF PYRIMIDINE-DERIVATIVES - ELECTRON IMPACT-INDUCED DECOMPOSITION OF MOLECULAR-IONS OF 4-AMINO-SUBSTITUTED AND 4-AMINO-DISUBSTITUTED 1,2-DIHYDRO-1-METHYLPYRIMIDIN-2-ONES

被引：7

作者：

PLAZIAK, AS ^{[1
]}

CELEWICZ, L ^{[1
]}

CISZEWSKI, K ^{[1
]}

GOLANKIEWICZ, K ^{[1
]}

机构：

[1] ADAM MICKIEWICZ UNIV POZNAN,FAC CHEM,GRUNWALDZKA 6,PL-68780 POZNAN,POLAND

来源：

ORGANIC MASS SPECTROMETRY | 1991年 / 26卷 / 10期

关键词：

D O I：

10.1002/oms.1210261008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electron impact (EI) mass spectra of fourteen 4-amino-substituted 1,2-dihydro-1-methylpyrimidin-2-ones are reported. The EI-induced decomposition of their molecular ions is significantly dependent on the chemical nature of the substituents. The routes of mass decomposition established suggest the presence of the tautomeric forms in the gas phase of some investigated compounds.

引用

页码：849 / 854

页数：6

共 17 条

[1]

CELEWICZ L, IN PRESS SYNTH COMMU

[2] CHEMOTHERAPEUTIC APPROACHES TO THE TREATMENT OF THE ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME (AIDS) [J].

DECLERCQ, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (09) :1561-1569

[3] MASS-SPECTRA OF BROMOHYDRINS OF URACIL DERIVATIVES [J].

DEZORMAZUR, M ;

GOLANKIEWICZ, K .

ORGANIC MASS SPECTROMETRY, 1987, 22 (04) :197-202

[4] SPECTROPHOTOMETRIC STUDIES OF NUCLEIC ACID DERIVATIVES AND RELATED COMPOUNDS AS A FUNCTION OF PH .2. NATURAL AND SYNTHETIC PYRIMIDINE NUCLEOSIDES [J].

FOX, JJ ;

SHUGAR, D .

BIOCHIMICA ET BIOPHYSICA ACTA, 1952, 9 (04) :369-384

[5]

HALL RH, 1971, MODIFIED NUCLEOSIDES, P295

[6] THE INFLUENCE OF ALKYL SUBSTITUENTS ON MASS FRAGMENTATION OF DINUCLEOTIDE ANALOGS CONTAINING 6-AZATHYMINE MOIETY [J].

JANKOWSKA, J ;

CELEWICZ, L ;

GOLANKIEWICZ, K .

ORGANIC MASS SPECTROMETRY, 1987, 22 (01) :52-54

[7] PREPARATION OF 1-(2,3-DIDEOXY-BETA-D-GLYCERO-PENT-2-ENOFURANOSYL)THYMINE (D4T)1 AND 2',3'-DIDEOXYADENOSINE (DDA) - GENERAL-METHODS FOR THE SYNTHESIS OF 2',3'-OLEFINIC AND 2',3'-DIDEOXY NUCLEOSIDE ANALOGS ACTIVE AGAINST HIV [J].

MANSURI, MM ;

STARRETT, JE ;

WOS, JA ;

TORTOLANI, DR ;

BRODFUEHRER, PR ;

HOWELL, HG ;

MARTIN, JC .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (20) :4780-4785

[8]

MATSUDA A, 1989, CHEM PHARM BULL, V37, P1659

[9] MASS-SPECTROMETRY OF 4N-PYRIMIDINYL AMINO-ACIDS [J].

PLAZIAK, AS ;

CELEWICZ, L ;

SPYCHALA, J ;

GOLANKIEWICZ, K .

ORGANIC MASS SPECTROMETRY, 1989, 24 (01) :55-58

[10] STABILIZATION OF EVEN-ELECTRON IONS BY CYCLIZATION OF SUBSTITUENTS ON 3N-NITROGENS AND 4N-NITROGENS IN 4N-SUBSTITUTED CYTOSINES [J].

PLAZIAK, AS ;

CELEWICZ, L ;

SPYCHALA, J ;

GOLANKIEWICZ, K .

ORGANIC MASS SPECTROMETRY, 1988, 23 (09) :654-658

← 1 2 →