ASYMMETRIC-SYNTHESIS OF (2R,6R) AND (2S,6S)-2,6-DIMETHYLPIPERAZINE

被引：10

作者：

MICKELSON, JW ^{[1
]}

JACOBSEN, EJ ^{[1
]}

机构：

[1] UPJOHN CO,DEPT MED CHEM,KALAMAZOO,MI 49001

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 01期

关键词：

D O I：

10.1016/0957-4166(94)00341-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title compounds were prepared via two efficient routes. The first sequence utilized a diastereospecific triflate alkylation in the key bond forming step while the second method relied on a novel intramolecular Mitsunobu reaction to set the required stereochemistry

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页码：19 / 22

页数：4

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