MACROCYCLIC TRICHOTHECENES FROM BRAZILIAN BACCHARIS SPECIES - FROM MICROANALYSIS TO LARGE-SCALE ISOLATION

被引：22
作者：
JARVIS, BB
机构：
[1] Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland
来源：
PHYTOCHEMICAL ANALYSIS | 1992年 / 3卷 / 06期
关键词：
COUNTERCURRENT CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLYETHYLENEIMINE SILICA; RORIDINS; TRICHOVERRINS; BACCHARINOIDS; SEPARATION METHODS;
D O I：
10.1002/pca.2800030602
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Two Brazilian species of Baccharis, B. megapotamica and B. coridifolia have been shown to contain a number of macrocyclic trichothecene antibiotics some of which are identical to those produced by the common soil fungi Myrothecium. A number of different materials and methods have been used in a large-scale (1800 kg) isolation procedure and in the chemical analysis of plant material, inter alia ferric gel precipitation, fractionation using polyethyleneimine impregnated silica gel and countercurrent chromatography.
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页码：241 / 249
页数：9
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