REDUCTION OF CEREBRAL BLOOD-FLOW IN CHRONIC-SCHIZOPHRENIA - RELATION TO AGE

被引：0
|
作者：
KANOH, M
KAMIOKA, Y
TAKAHASHI, S
机构：
[1] SAKU CENT HOSP,DEPT PSYCHIAT,USUDA,JAPAN
[2] TAKASAKI NATL HOSP,DEPT PSYCHIAT,TAKASAKI,JAPAN
来源：
JAPANESE JOURNAL OF PSYCHIATRY AND NEUROLOGY | 1992年 / 46卷 / 01期
关键词：
REGIONAL CEREBRAL BLOOD FLOW; XE-133 INHALATION TECHNIQUE; CHRONIC SCHIZOPHRENIA; AGE;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The effect of age on resting-state cerebral blood flow (CBF) was studied in 40 medicated patients with chronic schizophrenia aged 20 to 57 and 32 age- and sex-matched normal controls, using the regional CBF with the xenon-133 inhalation technique. Global CBF (average of 16 cerebral regions) and the left prefrontal flow ratio (left prefrontal/global CBF) were significantly lower in schizophrenics aged 20-29 than in age-matched controls. Both global CBF and the left prefrontal flow ratio correlated with age in controls, but neither of such correlations was found in schizophrenics. Therefore, the CBF deficits in chronic schizophrenia appear to be unaffected by the aging process.
引用
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页码：113 / 119
页数：7
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