AGING, OSCILLATIONS AND EFFICIENCY

被引：6
作者：
GILBERT, DA [1 ]
机构：
[1] UNIV WITWATERSRAND,SCH MED,DEPT BIOCHEM MED,WITWATERSRAND 2050,SOUTH AFRICA
来源：
BIOSYSTEMS | 1995年 / 36卷 / 01期
关键词：
AGING; CELLULAR OSCILLATIONS; RESONANCE; COUPLING; GLYCOLYTIC EFFICIENCY;
D O I：
10.1016/0303-2647(94)01491-O
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The phenomenon of ageing still defies understanding. Theoretical studies have indicated that gycolysis is more efficient at maintaining a high ATP/ADP ratio when oscillating at its resonant frequency. Earlier, it was proposed that the differentiated state results from the establishment of a stable pattern of temporal organisation. It is now suggested that ageing involves a decrease in efficiency due to the detuning of oscillating glycolysis as a result of frequency locking with other cellular oscillations in the differentiated state.
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页码：1 / 5
页数：5
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