PRENATAL-DIAGNOSIS OF MOSAIC 4P - IN A FETUS WITH TRISOMY-21

被引：4
作者：
PHELAN, MC [1 ]
SAUL, RA [1 ]
GAILEY, TA [1 ]
SKINNER, SA [1 ]
机构：
[1] GREENVILLE GEN HOSP,GREENVILLE,SC
来源：
PRENATAL DIAGNOSIS | 1995年 / 15卷 / 03期
关键词：
WOLF-HIRSCHHORN SYNDROME; DEL(4)(P16); 4P-; MOSAICISM; TRISOMY; 21; PRENATAL DIAGNOSIS;
D O I：
10.1002/pd.1970150311
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Mosaicism for the Wolf-Hirschhorn syndrome, del(4)(p16), is extremely rare and has not been reported in association with a numerical chromosome abnormality. We report the prenatal diagnosis of mosaic del(4)(p16) and non-mosaic trisomy 21 in a 16-week female fetus. The pregnancy ended in spontaneous abortion at 34 weeks secondary to fetal demise. The fetus had features of both 4p - and trisomy 21.
引用
收藏
页码：274 / 277
页数：4
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