AN APPROACH TO FEATURES RESPONSIBLE FOR THE OBTENTION OF HIGH EE WITH A HIGHLY ENANTIOSELECTIVE NADH MODEL

被引：27

作者：

COMBRET, Y

DUFLOS, J

DUPAS, G

BOURGUIGNON, J

QUEGUINER, G

机构：

[1] URA 1429 CNRS/Institut National des Sciences Appliquées, 76131 Mont Saint Aignan

来源：

TETRAHEDRON | 1993年 / 49卷 / 24期

关键词：

NADH MODELS; ASYMMETRIC REDUCTION; FREE ROTATING ABILITY; ENTROPY;

D O I：

10.1016/S0040-4020(01)82373-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A study of the reactivity of several NADH models with free, restricted or suppressed rotating ability of the amide carbonyl group suggests that the main factor responsible for the high e.e. obtained (94 %) with a cyclized reagent is an entropy feature.

引用

页码：5237 / 5246

页数：10

共 16 条

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