HIGHLY PRACTICAL, ENANTIOSPECIFIC SYNTHESIS OF THE CYCLOHEXYL FRAGMENT OF THE IMMUNOSUPPRESSANT FK-506

被引：19
|
作者：
KOTSUKI, H
NISHIKAWA, H
MORI, Y
OCHI, M
机构：
[1] Department of Chemistry, Faculty of Science, Kochi University, Kochi 780, Akebono-cho
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 18期
关键词：
D O I：
10.1021/jo00044a051
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：5036 / 5040
页数：5
相关论文
共 50 条
  • [31] ALLOGRAFT AND XENOGRAFT ACCEPTANCE UNDER FK-506 AND OTHER IMMUNOSUPPRESSANT TREATMENT
    STARZL, TE
    MURASE, N
    DEMETRIS, AJ
    ILDSTAD, S
    RICORDI, C
    TRUCCO, M
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1993, 685 : 46 - 51
  • [32] THE IMMUNOSUPPRESSANT FK-506 PREVENTS PROGRESSION OF DIABETES IN NONOBESE DIABETIC MICE
    KURASAWA, K
    KOIKE, T
    MATSUMURA, R
    TAKABAYASHI, K
    TOMIOKA, H
    ITO, I
    YOSHIDA, S
    CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 1990, 57 (02): : 274 - 279
  • [33] PRACTICAL ASPECTS OF FK-506 ANALYSIS (PITTSBURGH EXPERIENCE)
    WARTY, VS
    VENKATARAMANAN, R
    ZENDEHROUH, P
    MEHTA, S
    MCKAVENEY, T
    FLOWERS, J
    ZUCKERMAN, S
    KRAJAK, A
    ZEEVI, A
    FUNG, J
    TODO, S
    STARZL, TE
    TRANSPLANTATION PROCEEDINGS, 1991, 23 (06) : 2730 - 2731
  • [34] THERAPEUTIC EFFECT OF A NEW IMMUNOSUPPRESSANT, FK-506, ON VASOSPASM AFTER SUBARACHNOID HEMORRHAGE
    NISHIZAWA, S
    PETERSON, JW
    SHIMOYAMA, I
    IWASAKI, K
    UEMURA, K
    WEIR, BK
    CHYATTE, D
    NEUROSURGERY, 1993, 32 (06) : 986 - 992
  • [35] DISCOVERY OF FK-506, A NOVEL IMMUNOSUPPRESSANT ISOLATED FROM STREPTOMYCES-TSUKUBAENSIS
    GOTO, T
    KINO, T
    HATANAKA, H
    NISHIYAMA, M
    OKUHARA, M
    KOHSAKA, M
    AOKI, H
    IMANAKA, H
    TRANSPLANTATION PROCEEDINGS, 1987, 19 (05) : 4 - 8
  • [36] A MECHANISTIC STUDY OF THE FK-506 TRICARBONYL SYSTEM REARRANGEMENT - SYNTHESIS OF C.9 LABELED FK-506
    ASKIN, D
    REAMER, RA
    JOE, D
    VOLANTE, RP
    SHINKAI, I
    TETRAHEDRON LETTERS, 1989, 30 (45) : 6121 - 6124
  • [37] ASPECTS OF AN APPROACH TOWARD THE SYNTHESIS OF FK-506
    IRELAND, RE
    VANASSE, B
    WIPF, P
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1990, 199 : 7 - CARB
  • [38] INITIAL EXPERIENCE WITH FK-506 AS AN IMMUNOSUPPRESSANT FOR NONHUMAN PRIMATE RECIPIENTS OF CARDIAC ALLOGRAFTS
    FLAVIN, T
    IVENS, K
    WANG, J
    GUTIERREZ, J
    HOYT, EG
    BILLINGHAM, M
    MORRIS, RE
    TRANSPLANTATION PROCEEDINGS, 1991, 23 (01) : 531 - 532
  • [39] PHARMACOKINETICS OF FK-506, A NOVEL IMMUNOSUPPRESSANT, AFTER INTRAVENOUS AND ORAL ADMINISTRATIONS TO RATS
    TAKADA, K
    USUDA, H
    OHHASHI, M
    YOSHIKAWA, H
    MURANISHI, S
    TANAKA, H
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1991, 14 (01): : 34 - 42
  • [40] THE EFFECT OF THE IMMUNOSUPPRESSANT FK-506 ON ALTERNATE PATHWAYS OF T-CELL ACTIVATION
    BIERER, BE
    SCHREIBER, SL
    BURAKOFF, SJ
    EUROPEAN JOURNAL OF IMMUNOLOGY, 1991, 21 (02) : 439 - 445
12345