ZOTEPINE IN THE TREATMENT OF SCHIZOPHRENIC-PATIENTS WITH PREVAILINGLY NEGATIVE SYMPTOMS - A DOUBLE-BLIND TRIAL VS HALOPERIDOL

被引：80
作者：
BARNAS, C
STUPPACK, CH
MILLER, C
HARING, C
SPERNERUNTERWEGER, B
FLEISCHHACKER, WW
机构：
[1] Biological Psychiatry Research Unit, Department of Psychiatry, University of Innsbruck
来源：
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1992年 / 7卷 / 01期
关键词：
D O I：
10.1097/00004850-199200710-00003
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Zotepine, a neuroleptic agent with additional 5-HT2 blocking properties, was compared with haloperidol in the treatment of schizophrenic patients with predominantly negative symptoms using a double-blind design. During the investigation period zotepine treated patients showed significant improvements in all rating instruments whereas haloperidol treated patients did not. Patients in the zotepine group developed fewer clinical side effects. The results of the presented study confirm the positive impressions gained in earlier open trials with zotepine.
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页码：23 / 27
页数：5
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