QUANTITATIVE-EVALUATION OF 2 PATHWAYS FOR ETHANOLAMINE PHOSPHOGLYCERIDE BIOSYNTHESIS IN RAT-BRAIN INVIVO

被引:6
作者
ORLANDO, P [1 ]
ARIENTI, G [1 ]
MASSARI, P [1 ]
PORCELLATI, G [1 ]
ROBERTI, S [1 ]
机构
[1] UNIV PERUGIA,SCH MED,DEPT BIOCHEM,I-06100 PERUGIA,ITALY
关键词
D O I
10.1007/BF00964437
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[3H]Ethanolamine and [32P]orthophosphate were injected intraventricularly into adult female rats. At varying time intervals after the injection (1-10 min), the animals were killed by means of a microwave apparatus, and phosphorylethanolamine and ethanolamine phosphoglycerides were extracted from the brains and counted after separation. The kinetic constants for phosphorylethanolamine incorporation into ethanolamine lipids were calculated both from3H data and from32P data. From our results, it seems that base exchange reactions for ethanolamine incorporation into ethanolamine lipids are a pathway active in brain in vivo. © 1979 Plenum Publishing Corporation.
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页码:595 / 603
页数:9
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