Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one) cyclopropane

被引：2

作者：

Panwar, Hemant ^{[1
]}

Chaudhary, Nidhi ^{[2
]}

Singh, Sachi ^{[3
]}

Chawla, Amit ^{[4
]}

机构：

[1] Neelkanth Inst Technol, Dept Chem, Meerut 250110, Uttar Pradesh, India

[2] IIMT IET, Dept Chem, Meerut 250001, Uttar Pradesh, India

[3] Dr KNMIET, Dept Chem, Ghaziabad 201204, UP, India

[4] Global Coll Pharm, Dept Pharmaceut Chem, Anandpur Sahib, Punjab, India

来源：

JOURNAL OF THE KOREAN CHEMICAL SOCIETY-DAEHAN HWAHAK HOE JEE | 2011年 / 55卷 / 06期

关键词：

Bis-phenylarylidinylthiadiazolidinone cyclopropane; Antifungal; Antibacterial; Acute toxicity;

D O I：

10.5012/jkcs.2011.55.6.994

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Some novel heterocyclic derivatives of 1,1-bis(2-phenyl-5-arylidine-1,3-thiadiazolidin-4-one) cyclopropane 4(a-i) have been synthesized from cyclopropane dicarboxylic acid and substituted thiadiazole moieties. All the synthesized compounds have been characterized by elemental and spectral (I.R., H-1-NMR, Mass) analysis. Furthermore, above said compounds were screened for their antifungal and antibacterial activities. Compound 4c was found the most potent one which further evaluated for lesser toxicity test.

引用

页码：994 / 999

页数：6

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