Insulin related lipodystrophic lesions and hypoglycemia: Double standards?

被引：14

作者：

Gentile, Sandro ^{[1
,3
]}

Strollo, Felice ^{[2
]}

Della Corte, Teresa ^{[1
]}

Marino, Giampiero ^{[1
]}

Guarino, Giuseppina ^{[1
]}

机构：

[1] Campania Univ Luigi Vanvitelli, Dept Internal Med, Naples, Italy

[2] San Raffaele Termini Inst, Endocrinol & Diabet, Rome, Italy

[3] AMD Med Assoc Diabetol, Study Grp Inject Tech, Naples, Italy

来源：

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS | 2018年 / 12卷 / 05期

关键词：

Diabetes; Insulin; Injection technique; Lipodystrophy; Lipohypertrophy;

D O I：

10.1016/j.dsx.2018.04.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lipohypertophy (LH) is the most common skin complication of incorrect injection technique which does not only represent an aesthetic defect but also severely disrupts insulin pharmacokinetics/pharmacodynamics. As a consequence of that, hormone release is delayed and unexplained/unpredictable hypoglycemia occurs, both deteriorating metabolic control while negatively affecting adherence to treatment and quality of life. The economic burden due to unwanted intra-LH injections is accounted for by inappropriately high insulin requirements, increased emergency-related hospitalizations, and loss of work days. Greater attention has to be paid by diabetes care teams to education programs with periodic refreshers to achieve better metabolic control and reduce the economic burden of diabetes. (c) 2018 Diabetes India. Published by Elsevier Ltd. All rights reserved.

引用

页码：813 / 818

页数：6

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