CONFORMATIONAL ASPECTS OF LOCAL ANESTHETICS

被引:9
作者
BOOTS, MR
BOOTS, SG
机构
[1] Department of Chemistry and Pharmaceutical Chemistry, School of Pharmacy, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia
关键词
3‐exo‐(N; N‐Dimethylaminomethyl‐2‐norbornanyl)4‐n‐butoxybenzoate epimers—synthesis; Anesthetics; local—conformational aspects; IR spectrophotometry—structure; NMR spectroscopy—structure; Pharmacological screening—local anesthetics; UV spectrophotometry—structure;
D O I
10.1002/jps.2600580505
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The syntheses of two epimers of 3‐exo‐(N,N‐dimethylaminomethyl‐2‐norbornanyl)4‐n‐butoxybenzoate are described. The results of several assays of local anesthetic activity are discussed. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company
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页码:553 / &
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