Erythropoietin in ophthalmology: A literature review

被引：25
作者：
Aghdam, Kaveh Abri [1 ]
Sanjari, Mostafa Soltan [1 ]
Falavarjani, Khalil Ghasemi [1 ,2 ]
机构：
[1] Iran Univ Med Sci, Rassoul Akram Hosp, Eye Res Ctr, Tehran, Iran
[2] UCLA, Doheny Eye Inst, Los Angeles, CA USA
来源：
JOURNAL OF CURRENT OPHTHALMOLOGY | 2016年 / 28卷 / 01期
关键词：
Erythropoietin; Neuroprotection; Apoptosis;
D O I：
10.1016/j.joco.2016.01.008
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To review the current literature on ocular application of erythropoietin (EPO). Methods: A comprehensive search was performed on Pubmed and Scopus databases. All selected articles were reviewed thoroughly by the authors to review current applications of the EPO in ocular diseases. Results: Various aspects of administration of EPO for different ischemic, traumatic, vascular, and degenerative disorders have been explained. The articles are generally preclinical with few small studies reporting clinical outcomes. Conclusion: EPO has been used for the treatment of different ophthalmic conditions with promising results. Further studies are needed to elaborate the role of EPO in management of ocular diseases. Copyright (c) 2016, Iranian Society of Ophthalmology. Production and hosting by Elsevier B.V.
引用
收藏
页码：5 / 11
页数：7
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