STARTING THE CELL-CYCLE - WHATS THE POINT

被引：106
作者：
CROSS, FR
机构：
[1] The Rockefeller University, New York, NY 10021-6390
来源：
CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 06期
关键词：
D O I：
10.1016/0955-0674(95)80062-X
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Early work on regulation of the budding yeast cell cycle defined a critical regulatory step called 'Start', considered to represent cell cycle commitment. Recent work has defined the probable molecular basis of Start to be activation of Cln-Cdc28 protein kinase complexes. Cln-Cdc28 kinases may directly regulate many cell cycle processes, including some classically considered to be 'post-Start'. Specialization of function among the three genetically redundant CLN genes is becoming apparent.
引用
收藏
页码：790 / 797
页数：8
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