ANALYSIS OF HEPATITIS-C VIRUS ISOLATES AMONG HEALTHY BLOOD-DONORS AND DRUG-ADDICTS IN CHIANG-MAI, THAILAND

被引：57

作者：

APICHARTPIYAKUL, C

CHITTIVUDIKARN, C

MIYAJIMA, H

HOMMA, M

HOTTA, H

机构：

[1] KOBE UNIV,SCH MED,DEPT MICROBIOL,CHUO KU,KOBE 650,JAPAN

[2] CHIANG MAI UNIV,FAC MED,DEPT MICROBIOL,CHIANG MAI 50002,THAILAND

[3] NO DRUG DEPENDENT TREATMENT CTR,CHIANG MAI 50150,THAILAND

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1994年 / 32卷 / 09期

关键词：

D O I：

10.1128/JCM.32.9.2276-2279.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Hepatitis C virus (HCV) isolates obtained from 25 anti-HCV antibody-positive healthy blood donors and 29 drug addicts in Chiang Mai, Thailand, were analyzed. HCV RNA was detected in 23 blood donor samples (92%) and 24 drug addict blood samples (83%) by PCR for a portion of the NS5 region. Subtype analysis revealed that HCV type 3a (HCV-3a) was the prevailing subtype (30%), which was followed in prevalence by HCV-1a (21%), -1b (13%), -3b (13%), and -6a (2%). Six (13%) of the 47 isolates showed low sequence similarities with known types and subtypes. The sequence variants could be grouped into four branches in a molecular evolutionary phylogenetic tree.

引用

页码：2276 / 2279

页数：4

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