Electrostatic effects in biological molecules

被引:59
作者
Bashford, Donald [1 ]
机构
[1] Scripps Clin, Res Inst, Dept Mol Biol, 10666 North Torrey Pines Rd, La Jolla, CA 92037 USA
关键词
D O I
10.1016/0959-440X(91)90058-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Accounting for polarization effects by either microscopic or macroscopic methods has been an important theme in recent theoretical research on electrostatics in biological molecules. This review covers these efforts and related experimental work.
引用
收藏
页码:175 / 184
页数:10
相关论文
共 85 条
[1]   PROTEIN STABILITY AND ELECTROSTATIC INTERACTIONS BETWEEN SOLVENT EXPOSED CHARGED SIDE-CHAINS [J].
AKKE, M ;
FORSEN, S .
PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1990, 8 (01) :23-29
[2]   COMPUTER-SIMULATIONS OF THE DIELECTRIC-PROPERTIES OF WATER - STUDIES OF THE SIMPLE POINT-CHARGE AND TRANSFERABLE INTERMOLECULAR POTENTIAL MODELS [J].
ALPER, HE ;
LEVY, RM .
JOURNAL OF CHEMICAL PHYSICS, 1989, 91 (02) :1242-1251
[3]  
ANDERSON CF, 1990, ANNU REV BIOPHYS BIO, V19, P423
[4]   PH-INDUCED DENATURATION OF PROTEINS - A SINGLE SALT BRIDGE CONTRIBUTES 3-5 KCAL MOL TO THE FREE-ENERGY OF FOLDING OF T4-LYSOZYME [J].
ANDERSON, DE ;
BECKTEL, WJ ;
DAHLQUIST, FW .
BIOCHEMISTRY, 1990, 29 (09) :2403-2408
[5]   MOLECULAR-DYNAMICS SIMULATION OF DIELECTRIC-PROPERTIES OF WATER [J].
ANDERSON, J ;
ULLO, JJ ;
YIP, S .
JOURNAL OF CHEMICAL PHYSICS, 1987, 87 (03) :1726-1732
[6]  
[Anonymous], 1986, NUMERICAL RECIPES
[7]  
AQVIST J, 1989, BIOCHEMISTRY-US, V28, P4680
[8]   WHY PREFERENTIAL HYDRATION DOES NOT ALWAYS STABILIZE THE NATIVE STRUCTURE OF GLOBULAR-PROTEINS [J].
ARAKAWA, T ;
BHAT, R ;
TIMASHEFF, SN .
BIOCHEMISTRY, 1990, 29 (07) :1924-1931
[9]   PREFERENTIAL INTERACTIONS DETERMINE PROTEIN SOLUBILITY IN 3-COMPONENT SOLUTIONS - THE MGCL2 SYSTEM [J].
ARAKAWA, T ;
BHAT, R ;
TIMASHEFF, SN .
BIOCHEMISTRY, 1990, 29 (07) :1914-1923
[10]   PKAS OF IONIZABLE GROUPS IN PROTEINS - ATOMIC DETAIL FROM A CONTINUUM ELECTROSTATIC MODEL [J].
BASHFORD, D ;
KARPLUS, M .
BIOCHEMISTRY, 1990, 29 (44) :10219-10225